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. 2014 Sep 12;9(9):e107550. doi: 10.1371/journal.pone.0107550

Figure 4. Urinary ORM1 as a potential biomarker for CHF.

Figure 4

(A) ELISA was used to quantify urinary ORM1 levels in 176 patients with CHF and 62 healthy controls. The expression level of ORM1 in different NYHA functional classification of CHF. *P <0.05 compared with control group; **P <0.05 compared with CHF I; ***P <0.05 compared with CHF III. (B) ROC curve of urinary ORM1 as a detection marker for CHF was based on a series of 238 urine samples. The optimal cut off was 2484.98 ng/mg, and the area under the ROC curve (AUC) for diagnosis of CHF was 0.892 (95% confidence interval (CI) 0.848–0.936).