Table 2. Identification of differentially expressed proteins in urine from chronic heart failure and normal control.
Master number | Accession No. | Gene Name | Protein molecular weight | Protein PI | Pep. Counta | Total ion score | Fold changesb | Overall trendc |
117 | P07911 | UMOD | 72451.4 | 5.05 | 9 | 518 | −12.77±3.46 | down |
133 | P07911 | UMOD | 72451.4 | 5.05 | 9 | 323 | −10.37±3.18 | down |
279 | P12830 | CDH1 | 97852 | 4.58 | 3 | 212 | 3.15±0.29 | up |
510 | P01042 | KNG1 | 72995.6 | 6.34 | 7 | 263 | −2.54 ±0.33 | down |
671 | P04745 | AMY1A | 58415.2 | 6.47 | 7 | 213 | −3.05±2.19 | down |
672 | P02774 | GC | 54525.6 | 5.4 | 3 | 134 | −3.33±1.26 | down |
697 | P04746 | AMY2A | 58354.3 | 6.6 | 8 | 106 | −2.45±1.06 | down |
700 | P04746 | AMY2A | 58354.3 | 6.6 | 8 | 215 | −2.33±0.52 | down |
822 | P02768 | ALB | 71317.2 | 5.92 | 8 | 208 | −4.33±0.51 | down |
827 | P02768 | ALB | 71317.2 | 5.92 | 9 | 229 | −6.31±1.21 | down |
850 | P02768 | ALB | 71317.2 | 5.92 | 7 | 163 | −6.24±0.89 | down |
924 | P25311 | AZGP1 | 34079 | 5.57 | 5 | 265 | 7.31±1.54 | up |
945 | P25311 | AZGP1 | 34079 | 5.57 | 4 | 245 | 7.55±1.89 | up |
952 | P25311 | AZGP1 | 34079 | 5.57 | 6 | 349 | 7.46±2.27 | up |
967 | P02763 | ORM1 | 23724.8 | 4.93 | 3 | 302 | 14.81±3.49 | up |
978 | P30740 | SERPINB1 | 42828.7 | 5.9 | 5 | 233 | −3.96±1.12 | down |
1086 | Q14624 | ITIH4 | 103521.1 | 6.51 | 4 | 189 | −3.96±1.23 | down |
1094 | Q14624 | ITIH4 | 103521.1 | 6.51 | 5 | 212 | −2.89±0.63 | down |
1238 | P02760 | AMBP | 39886.3 | 5.95 | 4 | 298 | 5.63±2.03 | up |
1266 | P00734 | F2 | 71474.7 | 5.64 | 3 | 167 | −4.55±1.96 | down |
1362 | P01842 | IGLC1 | 11400.6 | 6.92 | 1 | 32 | −11.72±3.69 | up |
1403 | P01834 | IGKC | 11772.7 | 5.58 | 1 | 94 | 17.63±5.67 | up |
1527 | P05937 | CALB1 | 30291.1 | 4.7 | 3 | 77 | −4.09±0.86 | down |
1529 | P01834 | IGKC | 11772.7 | 5.58 | 1 | 50 | 4.43±1.49 | up |
1621 | P98160 | HSPG2 | 479220.5 | 6.06 | 6 | 253 | −2.89±1.34 | down |
1675 | P17900 | GM2A | 21280.9 | 5.17 | 2 | 152 | 6.31±3.63 | up |
1681 | O00187 | MASP2 | 77224.2 | 5.47 | 7 | 351 | −3.15±1.74 | down |
1726 | P13987 | CD59 | 14795 | 6.02 | 1 | 59 | 2.99±1.36 | down |
Calculated by amino acid count.
Fold changes of spot intensities represented as mean ± SD.
up: up-regulated in the heart failure group. down: down-regulated in the heart failure group.