. Author manuscript; available in PMC: 2015 Sep 1.

Published in final edited form as: Clin Colorectal Cancer. 2014 Jun 26;13(3):192–198. doi: 10.1016/j.clcc.2014.05.003

Table 2.

Clinical factors associated with the development of any grade 3 or higher toxicity (hematologic or non hematologic).

	Patients experiencing ≥ grade 3 hematologic/non-hematologic toxicity n=50 (43%)	Patients without ≥ grade 3 hematologic/non-hematologic toxicity n=67 (57%)	P Value

Median Age (range)	73 (65–85)	73 (add 65–85)	0.91

PS at initiation^* n(%):
0–1	44 (88%)	45 (67%)	0.011^*
≥2	5(10%)	20(29%)

Time on therapy (full cohort)	144.6 days	56.8 days	<0.0001^*

Time on therapy (single agent)	179 days	56.5 days	0.0004^*

Time on therapy (combination with chemotherapy)	141.2 days	75.6 days	0.008^*

Statistically significant findings.