Figure 1. Maternal plasma copeptin is significantly elevated throughout pregnancies that eventually develop preeclampsia.

(A) Maternal plasma copeptin concentrations throughout gestation from women with normal pregnancies and pregnancies that eventually developed preeclampsia. (B) Comparison of plasma copeptin concentrations within each trimester of pregnancy among control pregnancies, pregnancies that eventually developed preeclampsia, and in non-pregnant women (n=33). (C) Maternal plasma cystatin C within each trimester from pregnancies with and without preeclampsia. (D) Plasma LNPEP within each trimester from pregnancies with and without preeclampsia. (E) Plasma sFLT-1 within each trimester from pregnancies with and without preeclampsia. Data points all represent individual maternal blood samples from control pregnancies n=26, 19, and 38, and preeclamptic pregnancies n=20, 20, and 50 for first, second and third trimesters, respectively. Boxes illustrate median, 25^th and 75^th percentiles, and whiskers illustrate 10^th and 90^th percentiles. *p<0.05.