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Immunomodulatory role of HDL at the signaling level. T cells from young and elderly individuals were reincubated with 50 μg/ml corresponding HDL for the indicated time points and tested by Western blotting for the phosphorylation status of key TcR/CD28 signaling molecules. The phosphorylation of Lck, ERK1/2, and Akt was tested in young (a) and elderly individuals (b)
