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. 2014 Aug 28;14:192. doi: 10.1186/s12862-014-0192-1

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© Guan et al.; licensee BioMed Central Ltd. 2014

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Transcriptional activity of HIF-αs under normoxic and hypoxic conditions. Each HIF-1α and HIF-2α was found to upregulate luciferase activity under normoxia, and the luciferase activity of HIF-1αB was high even under normoxia.