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. Author manuscript; available in PMC: 2015 Aug 1.
Published in final edited form as: Curr Opin Endocrinol Diabetes Obes. 2014 Aug;21(4):287–292. doi: 10.1097/MED.0000000000000076

Table 1. Goals of biomarkers in Type 1 diabetes clinical trials.

• Early detection of insulitis
• Prediction of development of overt diabetes in at risk subjects
• Identification of responders to treatment
• Direct measurement of β cell mass and death