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. Author manuscript; available in PMC: 2014 Sep 13.
Published in final edited form as: J Am Chem Soc. 2009 Jun 17;131(23):8252–8261. doi: 10.1021/ja9010095

Figure 11.

Figure 11

Structures of hIAPP1–19 (A), hIAPP (B), rIAPP (C), and rIAPP1–19 (D) showing the degree of occlusion of the putative self-association site by the N-terminal loop in each structure. The hydrophobic residues that have been implicated in coiled-coil interactions stabilize the IAPP oligomer are colored in blue.