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. Author manuscript; available in PMC: 2014 Sep 13.
Published in final edited form as: J Am Chem Soc. 2008 Apr 30;130(20):6424–6429. doi: 10.1021/ja710484d

Figure 1.

Figure 1

Dye leakage from POPG vesicles induced by the full-length hIAPP and the hIAPP1–19 fragment. Carboxyfluorescein containing POPG liposomes (1.5 mM) were added to 250 nM (A) or 1 mM (B) solutions of either full-length hIAPP or the hIAPP1–19 fragment along with the listed concentrations of dye-free POPG liposomes. The fraction of dye leaked was recorded at 100 s. Each experiment was repeated three times; error bars indicate 1 standard deviation from the average. All experiments were performed in 50 mM sodium phosphate buffer at pH 7.5.