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Structural comparison of tandem phosphatase domains of RPTPs. Superposition of the structures of the tandem phosphatase domains of PTPσ (green), LAR (purple), CD45 (blue), and PTPγ (orange). Amino acids involved in interdomain interactions for PTPσ are shown to the right of the D1–D2 structures. For all structures the D1 and D2 domains are shown in dark and light shades of color, respectively
