Figure 4.

The association between number of galanin-immunoreactive neurons in the intermediate nucleus and sleep fragmentation does not differ by the presence/absence of Alzheimer's disease. (A) Association between galanin-immunoreactive neuron counts and sleep fragmentation considering participants without Alzheimer’s disease who died within 1 year of actigraphy (n = 13). (B) Participants with Alzheimer’s disease who died within 1 year of actigraphy (n = 6). All panels show partial regression plots of models adjusted for age and sex. r indicates the partial correlation coefficient between the number of galanin-immunoreactive neurons and sleep fragmentation measured using k_RA. The association between the number of galanin-immunoreactive neurons and sleep fragmentation does not differ in those with and without Alzheimer’s disease (interaction P = 0.64). AD = Alzheimer’s disease; Gal = galanin; IN = intermediate nucleus.