Table 1.
Comparison of participants in whom tissue blocks containing the intermediate nucleus were and were not available
| Characteristics | Intermediate nucleus not available | Intermediate nucleus available | P-value |
|---|---|---|---|
| (n = 128) | (n = 45) | ||
| Age at death (years) | 89.5 (85.2–93.6) | 89.4 (85.2–93.5) | 0.73 |
| Male sex | 40 (31%) | 13 (29%) | 0.91 |
| Clinical Alzheimer’s disease | 52 (41%) | 12 (27%) | 0.14 |
| NIA-Reagan pathological classification for Alzheimer’s disease | No: 2 (2%) | No: 0 (0%) | 0.83 |
| Low: 46 (36%) | Low: 16 (36%) | ||
| Intermediate: 61 (48%) | Intermediate: 21 (47%) | ||
| High: 19 (15%) | High: 8 (18%) | ||
| Braak stage | 0: 2 (2%) | 0: 0 | 0.49 |
| I: 8 (6%) | I: 3 (7%) | ||
| II: 13 (10%) | II: 4 (9%) | ||
| III: 39 (30%) | III: 7 (16%) | ||
| IV: 39 (30%) | IV: 19 (42%) | ||
| V: 24 (19%) | V: 11 (24%) | ||
| VI: 3 (2%) | VI: 1 (2%) | ||
| Months between actigraphy and death | 14.2 (7.3–26.0) | 15.5 (7.4–26.1) | 0.68 |
| Post-mortem interval | 6.3 (4.8–9.8) | 6.4 (4.8–9.7) | 0.45 |
| Sleep fragmentation (kRA) | 0.0327 (0.023–0.035) | 0.027 (0.023–0.030) | 0.55 |
| Self-report hours of sleep | 7.0 (6.0–8.0) | 7.0 (6.0–8.0) | 0.34 |
| Hours of sustained rest per day | 7.2 (6.0–8.3) | 7.1 (5.9–8.2) | 0.32 |
| Proportion of rest time spent in long bouts | 0.48 (0.38–0.55) | 0.49 (0.43–0.55) | 0.38 |
All values expressed as median (IQR) or n (%).