Comparison 4.

Aspirin 900 mg plus metoclopramide 10 mg versus active comparator

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Headache relief at 2 hours	2		Risk Ratio (M-H, Fixed, 95% CI)	Subtotals only
1.1 Sumartiptan 100 mg	2	523	Risk Ratio (M-H, Fixed, 95% CI)	0.93 [0.79, 1.10]
2 Pain free at 2 hours	2		Risk Ratio (M-H, Fixed, 95% CI)	Subtotals only
2.1 Sumatriptan 100 mg	2	528	Risk Ratio (M-H, Fixed, 95% CI)	0.63 [0.45, 0.87]
3 Relief of associated symptoms at 2 hours	2		Risk Ratio (M-H, Fixed, 95% CI)	Subtotals only
3.1 Nausea	2	410	Risk Ratio (M-H, Fixed, 95% CI)	1.10 [0.83, 1.46]
3.2 Vomiting	2	67	Risk Ratio (M-H, Fixed, 95% CI)	10.59 [1.43, 78.64]
4 Persistence of associated symptoms after 2 hours	2		Risk Ratio (M-H, Fixed, 95% CI)	Subtotals only
4.1 Nausea	2	612	Risk Ratio (M-H, Fixed, 95% CI)	0.99 [0.83, 1.19]
4.2 Vomiting	2	608	Risk Ratio (M-H, Fixed, 95% CI)	0.63 [0.39, 1.02]