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. Author manuscript; available in PMC: 2014 Sep 13.
Published in final edited form as: Cochrane Database Syst Rev. 2010 Apr 14;(4):CD008041. doi: 10.1002/14651858.CD008041.pub2

Comparison 6.

Aspirin ± metoclopramide versus active comparator

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Use of rescue medication 4 Risk Ratio (M-H, Fixed, 95% CI) Subtotals only
 1.1 Aspirin versus sumatriptan 50 mg 2 726 Risk Ratio (M-H, Fixed, 95% CI) 1.09 [0.92, 1.29]
 1.2 Aspirin+met versus sumatriptan 100 mg 2 614 Risk Ratio (M-H, Fixed, 95% CI) 1.18 [1.01, 1.39]
2 Any adverse event within 24 hours 4 Risk Ratio (M-H, Fixed, 95% CI) Subtotals only
 2.1 Aspirin versus sumatriptan 50 mg 2 730 Risk Ratio (M-H, Fixed, 95% CI) 0.85 [0.61, 1.18]
 2.2 Aspirin+met versus sumatriptan 100 mg 2 617 Risk Ratio (M-H, Fixed, 95% CI) 0.66 [0.52, 0.84]