Summary of results C.
Relief of associated symptoms 2 hours after taking study medication
| Intervention | Studies | Attacks with symptom present | Treatment (%) | Placebo (%) | Relative risk (95% CI) | NNT |
|---|---|---|---|---|---|---|
| Nausea | ||||||
| Aspirin 1000 mg versus placebo | 4 | 878 | 56 | 44 | 1.3 (1.1 to 1.4) | 9.0 (5.6 to 22) |
| Aspirin 900 mg plus metoclopramide 10 mg versus placebo | 2 | 417 | 45 | 6 | 7.5 (4.2 to 14) | 2.6 (2.1 to 3.1) |
| Aspirin 900 mg plus metoclopramide 10 mg versus sumatriptan 100 mg | 2 | 410 | 35 | 31 | 1.1 (0.83 to 1.5) | Not calculated |
| Vomiting | ||||||
| Aspirin 1000 mg versus placebo | 3 | 139 | 73 | 66 | 1.1 (0.94 to 1.3) | Not calculated |
| Aspirin 900 mg plus metoclopramide 10 mg versus placebo | 2 | 59 | 46 | 0 | 17 (2.3 to 120) | 2.1 (1.5 to 3.7) [12 events] |
| Aspirin 900 mg plus metoclopramide 10 mg versus sumatriptan 100 mg | 2 | 67 | 33 | 0 | 11 (1.4 to 78) | 3.3 (2.1 to 7.4) [11 events] |
| Photophobia | ||||||
| Aspirin 1000 mg versus placebo | 5 | 1236 | 47 | 33 | 1.4 (1.2 to 1.6) | 7.7 (5.4 to 13) |
| Aspirin 1000 mg versus sumatriptan 50 mg | 2 | 575 | 60 | 66 | 0.91 (0.80 to 1.03) | Not calculated |
| Phonophobia | ||||||
| Aspirin 1000 mg | 5 | 1217 | 49 | 34 | 1.4 (1.3 to 1.7) | 6.6 (4.9 to 10) |
| Aspirin 1000 mg versus sumatriptan 50 mg | 2 | 540 | 63 | 65 | 0.98 (0.86 to 1.1) | Not calculated |