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. 2014 Apr 3;8(10):2116–2130. doi: 10.1038/ismej.2014.45

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Copyright © 2014 International Society for Microbial Ecology

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/3.0/

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HFD feeding and prebiotic treatment affect antimicrobial peptides in the intestine. Antibacterial peptide mRNA expression: (a) Regenerating islet-derived 3-gamma (RegIIIγ, encoded by Reg3g); (b) Phospholipase A2 group II (encoded by Pla2g2); (c) Lysozyme C (encoded by Lyz1); (d) α-defensins (encoded by Defa); and (e) Angiogenin 4 (encoded by Ang4) measured in the jejunum of control diet-fed mice (CT) (n=9), CT diet-fed mice treated with prebiotics (CT-Pre) (n=10), HFD-fed mice (HFD) (n=10) and HFD-fed mice treated with prebiotics (HFD-Pre) (n=10). Data are means±s.e.m. Data with different superscript letters are significantly different (P<0.05) according to a post hoc ANOVA one-way statistical analysis.