Table 1.
ICAM4 alleles identified in the present study
| Allele † | ISBT name | Nucleotide substitution (position) *
|
||||||
|---|---|---|---|---|---|---|---|---|
| 5′UTR
|
Exon 1
|
Intron 1 (IVS1)
|
Exon 2
|
Exon 3
|
||||
| -286C>T | c.188A>G (p.Lys63Arg) | c.299A>G (p.Gln100Arg) | IVS1+49A>C | IVS1+124C>T | c.545G>C (p.Arg182Pro) | c.773A>C (p.Lys258Thr) | ||
| KF712272 | LW*05 | C | A | A | A | C | G | A |
| KF725837 | NA | T | A | A | A | C | G | A |
| KF725836 | NA | C | G | A | A | C | G | A |
| KF725831 | LW*07 | C | A | G | A | C | G | A |
| KF725834 | NA | C | A | A | C | C | G | A |
| KF725835 | NA | C | A | A | A | T | G | A |
| KF725832 | NA | C | A | A | A | C | C | A |
| KF725833 | NA | C | A | A | A | C | G | C |
*
relative to NCBI Reference Sequence NG_007728.1 within the 1920 nucleotides of the ICAM4 gene. Numbering is according to ICAM4 Isoform 3 (NM_001039132.2, NP_001034221.1). Variant nucleotides are in bold
†
GenBank nucleotide database accession number
NA – Not applicable, because LW serology was not confirmed