. Author manuscript; available in PMC: 2015 Oct 1.

Published in final edited form as: Am J Cardiol. 2014 Jul 16;114(7):997–1002. doi: 10.1016/j.amjcard.2014.07.009

Table 3. Risk of subsequent cardiovascular events among participants with daily or weekly (vs. no) reported angina.

	Hospitalization for Angina		Revascularization		Myocardial Infarction		Heart Failure		Death
	HR (95%CI)^a	P- value	HR (95%CI)^a	P- value	HR (95%CI)^a	P- value	HR (95%CI)^a	P- value	HR (95%CI)^a	P- value
Unadjusted	3.3 (2.3, 4.7)	<.001	2.0 (1.3, 2.9)	0.001	1.3 (0.8, 2.3)	0.29	1.6 (1.0, 2.5)	0.03	1.5 (1.1, 2.0)	0.01
Model 1 ^b	2.5 (1.7, 3.7)	<.001	1.8 (1.1, 2.7)	0.01	1.0 (0.5, 1.7)	0.87	1.3 (0.8, 2.1)	0.25	1.5 (1.1, 2.0)	0.02
Model 2 ^c	2.4 (1.6, 3.6)	<.001	1.7 (1.1, 2.7)	0.01	1.0 (0.5, 1.7)	0.88	1.2 (0.7, 2.0)	0.47	1.4 (1.0, 1.9)	0.08
Model 3 ^d	2.4 (1.6, 3.6)	<.001	1.7 (1.1, 2.7)	0.02	0.9 (0.5, 1.7)	0.85	1.3 (0.8, 2.1)	0.32	1.4 (1.0, 2.0)	0.045

Hazard Ratio (HR) and 95% confidence interval (CI) for cardiovascular events in participants with daily or weekly angina compared to participants without angina at baseline.

Model 1 adjusts for age, sex, smoking, hypertension history, heart failure history, body mass index, diastolic blood pressure, beta-blocker use, calcium-channel blocker use, and nitrate use.

Model 2 adjusts for the factors in Model 1 + depressive symptoms.

Model 3 adjusts for the factors in Model 2 + treadmill exercise capacity, left ventricular ejection fraction, and inducible ischemia.