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. Author manuscript; available in PMC: 2015 Sep 1.
Published in final edited form as: Alcohol. 2014 Jul 14;48(6):543–549. doi: 10.1016/j.alcohol.2014.07.002

Figure 3. SUBSEQUENT 5-DAY TREATMENT.

Figure 3

Effects of clonidine (10, 20, 40, 80 µg/kg BW, IP) on 2-h alcohol intake by adult male P rats. Clonidine was injected on each of 5 consecutive days (Days 1–5) at 30 min prior to onset of a 2-h free-choice between alcohol (15% v/v) and water. Alcohol was not available on weekends. The Pre-Drug Day was a Friday preceding Drug Days 1–5 (Monday–Friday of the following week) and Post-Drug Days 3 and 4 were on Monday and Tuesday of the week following termination of clonidine treatment. ***p < 0.001 vs. saline control treatment, independent of drug treatment day.