Table 7.

The effects on organ weights and the relative organ weights of MLE in female SD rats ($\stackrel{-}{X}\pm \text{SD}$, g).

Parameters	Control group (n = 6)	Low dose group (n = 6)	Medium dose group (n = 6)	High dose group (n = 6)
Organ weight (g)
Heart	1.074 ± 0.162	1.059 ± 0.054	1.058 ± 0.100	1.092 ± 0.097
Liver	6.629 ± 0.449	7.320 ± 1.076	7.342 ± 0.747	7.215 ± 1.015
Spleen	0.484 ± 0.030	0.514 ± 0.058	0.470 ± 0.049	0.496 ± 0.073
Lung	1.230 ± 0.098	1.223 ± 0.084	1.256 ± 0.064	1.280 ± 0.116
kidney	1.751 ± 0.152	1.832 ± 0.169	1.875 ± 0.134	2.014 ± 0.227*
Brain	1.911 ± 0.054	1.905 ± 0.113	1.869 ± 0.084	1.905 ± 0.082
Adrenal gland	0.064 ± 0.013	0.082 ± 0.017	0.070 ± 0.012	0.084 ± 0.013*
Thymus	0.266 ± 0.052	0.282 ± 0.074	0.308 ± 0.065	0.264 ± 0.096
Uterus	0.726 ± 0.156	0.733 ± 0.107	0.756 ± 0.107	0.641 ± 0.184
Ovary	0.186 ± 0.025	0.194 ± 0.030	0.174 ± 0.036	0.195 ± 0.028
Fat	8.844 ± 2.096	9.452 ± 2.210	10.023 ± 4.202	8.612 ± 4.182
Organ/body weight ratio (mg/g)
Weight	283.2 ± 13.8	286.5 ± 14.2	289.0 ± 26.4	291.8 ± 35.2
Heart	3.791 ± 0.516	3.705 ± 0.283	3.666 ± 0.244	3.770 ± 0.440
Liver	23.404 ± 0.952	25.490 ± 2.803	25.445 ± 1.930*	24.696 ± 1.327
Spleen	1.709 ± 0.079	1.793 ± 0.171	1.630 ± 0.130	1.702 ± 0.146
Lung	4.341 ± 0.244	4.267 ± 0.190	4.364 ± 0.286	4.405 ± 0.269
kidney	6.190 ± 0.561	6.388 ± 0.388	6.503 ± 0.327	6.919 ± 0.411*
Brain	6.757 ± 0.252	6.667 ± 0.568	6.509 ± 0.622	6.608 ± 0.872
Adrenal gland	0.226 ± 0.043	0.286 ± 0.050	0.242 ± 0.035	0.294 ± 0.068
Thymus	0.937 ± 0.163	0.986 ± 0.254	1.064 ± 0.197	0.900 ± 0.299
Uterus	2.567 ± 0.557	2.563 ± 0.379	2.636 ± 0.438	2.190 ± 0.518
Ovary	0.659 ± 0.102	0.682 ± 0.137	0.608 ± 0.153	0.674 ± 0.095
Fat	31.288 ± 7.420	32.888 ± 6.624	33.915 ± 11.504	28.450 ± 11.684
Organ/brain weight ratio (g/g)
Brain	1.911 ± 0.054	1.905 ± 0.113	1.869 ± 0.084	1.905 ± 0.082
Heart	0.562 ± 0.081	0.559 ± 0.063	0.567 ± 0.060	0.573 ± 0.047
Liver	3.468 ± 0.195	3.857 ± 0.622	3.926 ± 0.318*	3.790 ± 0.526
Spleen	0.253 ± 0.011	0.270 ± 0.029	0.252 ± 0.026	0.261 ± 0.042
Lung	0.643 ± 0.050	0.643 ± 0.050	0.672 ± 0.023	0.673 ± 0.063
kidney	0.916 ± 0.075	0.966 ± 0.119	1.005 ± 0.084	1.057 ± 0.103*
Brain	0.033 ± 0.006	0.043 ± 0.010	0.037 ± 0.006	0.044 ± 0.005**
Adrenal gland	0.139 ± 0.024	0.149 ± 0.041	0.165 ± 0.033	0.139 ± 0.053
Thymus	0.380 ± 0.082	0.385 ± 0.049	0.406 ± 0.062	0.338 ± 0.104
Uterus	0.098 ± 0.014	0.102 ± 0.018	0.094 ± 0.022	0.103 ± 0.016
Ovary	4.645 ± 1.166	4.979 ± 1.183	5.390 ± 2.372	4.525 ± 2.194

∗Means P < 0.05; ∗∗means P < 0.01; n means the number of animals.