Table 4.
Adjusted odds ratios (OR) and respective 95% confidence intervals for the association between levels of lipids (mg/dL) and genotypes of LPL, apoE, and PPARα and infected symptomatic and asymptomatic L. infantum infection.
| Variable | Infected symptomatic infection | Infected asymptomatic infection | ||||
|---|---|---|---|---|---|---|
| OR∗ | 95% CI∗ | P value | OR∗ | 95% CI∗ | P value | |
| HindIII | ||||||
| H−/H− | 1.00 | 1.00 | ||||
| H+/H− | 6.37 | 0.84–83.4 | 0.083 | 2.04 | 0.49–10.4 | 0.435 |
| H+/H+ | 21.3 | 2.32–335.3 | 0.003 | 3.48 | 0.72–20.4 | 0.143 |
| PvuII | ||||||
| P1/P1 | 1.00 | 1.00 | ||||
| P1/P2 | 1.86 | 0.55–6.68 | 0.395 | 1.42 | 0.52–3.98 | 0.593 |
| P2/P2 | 0.71 | 0.10–5.28 | 1.000 | 1.20 | 0.18–7.81 | 1.000 |
| ApoE | ||||||
| E3/E4 | 1.00 | 1.00 | ||||
| E3/E3 | 2.66 | 0.52–16.1 | 0.312 | 0.91 | 0.28–2.93 | 1.000 |
| E2/E3 | 4.31 | 0.23–113.7 | 0.515 | 1.90 | 0.22 –25.3 | 0.825 |
| PPARα | ||||||
| Leu/Leu | 1.00 | 1.00 | ||||
| Leu/Val | 8.77 | 1.41–78.7 | 0.014 | 2.76 | 0.56–17.9 | 0.272 |
| TC | 0.99 | 0.97–1.01 | 0.301 | 1.00 | 0.99–1.01 | 0.787 |
| LDL-C | 0.99 | 0.97–1.01 | 0.353 | 1.01 | 0.99–1.02 | 0.414 |
| HDL-C | 0.84 | 0.71–0.96 | 0.006 | 0.92 | 0.84–0.99 | 0.027 |
| TAG | 1.02 | 1.00–1.03 | 0.021 | 1.00 | 0.99–1.01 | 0.597 |
| VLDL-C | 1.08 | 1.01–1.17 | 0.023 | 1.01 | 0.97–1.05 | 0.580 |
∗Adjusted for age (≤ or >20 years) and gender.
P values in bold indicate statistically significant differences.