Table 1.
Characteristics of the study patients (mean ± standard deviation, P value in an ANOVA).
| Status | Number of reports, (%) |
Age, years |
eGFR, mL/min per 1.73 m2 |
HbA1c, (%) |
25(OH)D, ng/mL |
25(OH)D >30 ng/mL, % |
Erythrocyte metformin, mg/L |
|---|---|---|---|---|---|---|---|
| All reports | 542 | 65.0 ± 11.2 | 44.3 ± 23.8 | 7.6 ± 1.8 | 25.7 ± 18.3 | 34.7 | 1.43 ± 1.45 |
| By CKD stage: | |||||||
| Stage 1 | 27 (5.0) | 59.9 ± 12.6 | 103.9 ± 11.1 | 7.5 ± 1.6 | 19.7 ± 15.9 | 22.2 | 0.91 ± 0.60 |
| Stage 2 | 95 (17.5) | 63.4 ± 12.0 | 72.0 ± 8.7 | 7.9 ± 1.9 | 22.7 ± 16.3 | 28.6 | 1.06 ± 0.61 |
| Stage 3 | 268 (49.4) | 66.8 ± 10.1 | 42.9 ± 8.3 | 7.8 ± 1.9 | 23.6 ± 16.8 | 30.6 | 1.31 ± 0.92 |
| Stage 4 | 105 (19.4) | 66.3 ± 2.0 | 22.3 ± 4.3 | 7.4 ± 1.4 | 28.7 ± 19.2 | 39.0 | 1.68 ± 1.99 |
| Stage 5 | 47 (8.7) | 57.8 ± 10.9 | 9.3 ± 3.1 | 6.3 ± 1.2 | 40.6 ± 21.6 | 68.1 | 2.58 ± 2.78 |
| P value | — | P < 0.0001 | P < 0.0001 | P < 0.0001 | P < 0.0001 | P < 0.0001 | P < 0.0001 |
| By vitamin D status: | |||||||
| Sufficiency | 188 (34.7) | 65.6 ± 10.9 | 38.3 ± 23.1 | 6.7 ± 1.0 | 45.9 ± 14.9 | — | 1.39 ± 0.97 |
| Insufficiency | 109 (20.1) | 63.4 ± 11.6 | 42.5 ± 22.4 | 7.3 ± 1.5 | 24.8 ± 2.7 | — | 1.31 ± 0.87 |
| Deficiency | 245 (45.2) | 65.3 ± 11.3 | 49.6 ± 23.8 | 8.4 ± 2.0 | 10.7 ± 4.8 | — | 1.51 ± 1.89 |
| P value | — | NS | P < 0.0001 | P < 0.0001 | P < 0.0001 | — | NS |