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. 2014 Aug 27;2014:836157. doi: 10.1155/2014/836157

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Copyright © 2014 Nan Zhang et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Altered frequency of TFH cells and levels of sera cytokines in MCD patients following treatment. The percentages of different subsets of TFH cells and the levels of sera cytokines were compared in MCD patients' pre- and posttreatment. Data are expressed as the mean % or concentrations of individual subjects from three separate experiments (n = 7 for a–f). (a) The percentages of CD4⁺CXCR5⁺ in the total CD3⁺CD4⁺ T cells in individual patients' pre- and posttreatment, (b) the percentage of CD4⁺CXCR5⁺PD-1⁺ TFH cells in total CD3⁺CD4⁺ T cells in individual patients' pre- and posttreatment, (c) the percentage of CD4⁺CXCR5⁺ICOS⁺ TFH cells in total CD3⁺CD4⁺ T cells in individual patients' pre- and posttreatment, and (d–f) the levels of IL-10, IL-4, and IL-21 in individual patients' pre- and posttreatment. The horizontal lines represent the median values.