Table 3.
Analysis of clinical characteristics between patients with TT and GT + GG genotypes.
| Variables | N (TT/GT + GG) | Genotype | Statistic tests | P | |
|---|---|---|---|---|---|
| TT | GT + GG | ||||
| Age (Mean ± SD, year) | 550/61 | 36.35 ± 14.04 | 37.41 ± 13.06 | t = 1.095 | 0.274 |
| Disease duration (Mean ± SD, year) | 550/61 | 10.43 ± 10.11 | 10.49 ± 9.38 | t = 0.045 | 0.964 |
| Age at onset (Mean ± SD, year) | 550/61 | 24.58 ± 10.24 | 26.82 ± 10.93 | t = 1.611 | 0.108 |
| Male | 348/44 | 23.85 ± 9.01 | 25.05 ± 9.68 | t = 0.824 | 0.411 |
| Female | 195/17 | 26.76 ± 11.14 | 31.42 ± 12.86 | t = 1.630 | 0.105 |
| Family history +: n (%) | 79/8 | 79 (90.80) | 8 (9.20) | χ 2 = 0.070 | 0.791 |
| Family history −: n (%) | 471/53 | 471 (89.89) | 53 (10.11) | ||
| PANSS (Mean ± SD) | |||||
| Total score | 533/60 | 80.16 ± 18.27 | 79.52 ± 19.30 | 0.258 | 0.796 |
| P subscore | 533/60 | 22.45 ± 7.26 | 21.88 ± 7.53 | 0.575 | 0.565 |
| N subscore | 533/60 | 18.33 ± 8.12 | 19.23 ± 6.95 | 0.831 | 0.406 |
| G subscore | 533/60 | 36.83 ± 8.92 | 36.38 ± 8.94 | 0.362 | 0.717 |
| BACS (Mean ± SD) | |||||
| Digit sequencing task | 185/24 | 15.58 ± 9.56 | 19.71 ± 8.18 | 2.016 | 0.045∗ |
| Category instances | 185/24 | 30.92 ± 12.67 | 31.79 ± 12.19 | 0.317 | 0.752 |
| Controlled oral word association test | 185/24 | 10.04 ± 6.07 | 10.04 ± 5.21 | 0.001 | 0.999 |
| List learning | 185/24 | 22.29 ± 12.61 | 21.33 ± 13.93 | 0.346 | 0.730 |
| Token motor task | 185/24 | 46.14 ± 11.83 | 46.29 ± 12.64 | 0.061 | 0.952 |
| Tower of London | 185/24 | 7.62 ± 6.85 | 7.50 ± 1.12 | 0.083 | 0.934 |
| Symbol coding | 185/24 | 21.12 ± 12.68 | 18.71 ± 12.31 | 0.881 | 0.379 |
*P < 0.05.
SD: standard deviation; PANSS: Positive and Negative Syndrome Scale; P: Positive scale; N: Negative scale; G: General Psychopathology scale; BACS: Brief Assessment of Cognition in Schizophrenia.