Figure 4.

Electron micrographs following ischemia and reperfusion. (a) Electron micrographs of cardiomyocyte in each group (upper: control, middle: 2 μg/mL of propofol, and lower: 10 μg/mL of propofol). Many wide I-bands (arrows) appeared in the myocyte with 0 and 10 μg/mL of propofol, whereas the I-band was not observed in 2 μg/mL of propofol. (b) Dense material deposits (arrows) in mitochondria appeared in all groups (upper: control, middle: 2 μg/mL of propofol, and lower: 10 μg/mL of propofol). However, the size and number of these deposits were less in mitochondria with 2 μg/mL of propofol than the other 2 groups. Moreover, structure of mitochondrial cristae was well preserved in group of 2 μg/mL, whilst it was significantly deformed with separation in other 2 groups.