Table 2.
Nephrotoxicity risk score.
Parameter | β coefficient | OR | 95% CI | Score |
---|---|---|---|---|
Nongenetic factors | ||||
Baseline Scr ≤1 mg/dL | 2.303 | 10.0 | 1.57~62.9 | 5 |
Cisplatin | 1.790 | 5.99 | 1.53~23.5 | 4 |
Coadministration of vinorelbine | 1.369 | 3.93 | 0.86~18.1 | 3 |
Smoking | 0.528 | 1.69 | 0.41~7.05 | 2 |
Number of cycles >4 | 0.098 | 1.10 | 0.47~4.93 | 1 |
Genetic factors | ||||
TP53 wild-type | 0.989 | 2.70 | 0.91~9.14 | 2 |
ERCC1 C118T wild-type | 0.990 | 2.70 | 0.90~8.35 | 2 |
OR: odds ratio; CI: confidence interval; Src: serum creatine.