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. Author manuscript; available in PMC: 2015 Nov 1.
Published in final edited form as: J Psychiatr Res. 2014 Jul 26;0:76–83. doi: 10.1016/j.jpsychires.2014.07.015

Table 1.

Study Characteristics for Trials Included in Meta-analyses

Study Active
Tx		 Control
Condition		 N Mean
Age		 Youth or
Adult
Sample		 Comorbid
Anxiety
Disorders		 Comorbid
Depressive
Disorders		 Outcome Measure Self v. Clinician
Report		 Approx
Contact
Hours		 Study
Quality		 Effect
Size
Behavior Therapy
Azrin et al., 1980 a BT MNP 32 27 Mixed NR NR number of daily hair pulling episodes Self-report 2 23 0.66
Ninan et al., 2000 b BT WL 10 33 Adult NR NR NIMH-TSS Clinician-report 9 19 1.94
Van Minnen et al., 2003 b BT PLBO 29 31 Mixed 3% 17% MGH-HPS Self-report 6 36 1.28
Diefenbach et al., 2006 BT SP 24 40 Adult 25% 21% MGH-HPS Self-report 8 30 0.56
Woods et al., 2006 BT WL 25 35 Adult 4% 32% MGH-HPS Self-report 10 28 2.14
Franklin et al., 2011 BT MAC 24 13 Youth 33% 13% NIMH-TSS Clinician-report 8 35 1.38
Keuthen et al., 2012 BT MAC 38 31 Adult 11% 0% NIMH-TSS Clinician-report 11 29 2.35
Serotonin Reuptake Inhibitors
Swedo et al., 1989 CMI DES 13 32 Mixed 8% 0% NIMH-TSS Clinician-report N/A 28 0.75
Christenson et al., 1991 FLUX PLBO 16 32 Adult 13% 19% weekly rating of hair pulling severity Self-report N/A 25 0.14
Streichenwien & Thronby, 1995 FLUX PLBO 16 39 Adult 31% 6% weekly severity of hair pulling episodes Self-report N/A 23 0.35
Ninan et al., 2000 b CMI PLBO 11 33 Adult NR NR NIMH-TSS Clinician-report N/A 20 0.61
Van Minnen et al., 2003 b FLUX PLBO 26 32 Mixed 0% 19% MGH-HPS Self-report N/A 38 0.54
Dougherty et al., 2006 SERT PLBO 36 29 Adult 30% 16% PITS Clinician-report N/A 27 0.17

Note: CMI = clomipramine, DES = desipramine, FLUX = fluoxetine, SERT = sertraline, PLBO = placebo, BT = behavior therapy, MNP = Mass Negative Practice, WL = waitlist, SP = Supportive psychotherapy, MAC = Minimal Attention Control, NAC = n-acetylcesteine, NR = not reported, NIMH-TSS = National Institute of Mental Health Trichotillomania Severity Scale, MGH-HPS = Massachusetts General Hospital Hair pulling Scale, PITS = Psychiatric Institute Trichotillomania Scale, N/A = not applicable.

a

used LOCF for participants without post-treatment assessment. Excluded two participants who did not use the same outcome metric.

b

PLBO group double counted for Van Minnen et al., 2003 and Ninan et al., 2000 due to small sample size of PLBO group