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. Author manuscript; available in PMC: 2015 Sep 1.
Published in final edited form as: Mol Cancer Res. 2014 Jul 17;12(9):1283–1291. doi: 10.1158/1541-7786.MCR-14-0080

Figure 4. Caspase-8 mediated apoptosis induced by TNF alpha is suppressed by NPMRAR.

Figure 4

U937 clones stably expressing NPM-RAR or vector only control were treated with 10 ng/mL TNF-alpha and 1 ug/mL CHX for 0, 45, 90, or 120 minutes. Conversion of substrate into luminescent product was determined using the caspase-Glo 8 detection kit. The assay was performed in triplicate.