Table.
Demographic and APOE genotype characteristics of demented and cognitively intact subjects in the nonagenarian (N-) and the general elderly (GE-) samples.
| Variable | Participants with Dementia |
Cognitively Intact Participants |
Statistic (df) | p-value |
|---|---|---|---|---|
| N-Sample | N = 37 | N = 75 | ||
| Age, mean (SD) | 93.4 (3.5) | 93.4 (3.3) | t = 0.01 (110) | 0.99 |
| Female, N (%) | 32 (86) | 51 (68) | Χ2 = 4.41 (1) | 0.04 |
| Years of education, mean (SD) | 3.5 (2.3) | 3.4 (3.0) | t = 0.51 (110) | 0.61 |
| APOE genotype, N (%) | ||||
| e2/e2 | 0 (0) | 0 (0) | ||
| e2/e3 | 0 (0) | 4 (5) | ||
| e2/e4 | 0 (0) | 1 (1) | ||
| e3/e3 | 29 (78) | 62 (83) | ||
| e3/e4 | 7 (19) | 8 (11) | ||
| e4/e4 | 1 (3) | 0 (0) | ||
| Presence of APOE-e4 allele, N (%) | Χ2 = 1.78 (1) | 0.18 | ||
| e4 | 8 (22) | 9 (12) | ||
| no e4 | 29 (78) | 66 (88) | ||
| GE-sample | N=53 | N=45 | ||
| Age, mean (SD) | 80.9 (6.5) | 78.6 (6.9) | t = 1.65 (96) | 0.102 |
| Female, N (%) | 40 (76) | 32 (71) | Χ2 = 0.24 (1) | 0.63 |
| Years of education, mean (SD) | 5.2 (4.1) | 3.9 (2.3) | t = 1.92 (96) | 0.06 |
| APOE genotype, N (%) | ||||
| e2/e2 | 1 (2) | 3 (7) | ||
| e2/e3 | 1 (2) | 0 (0) | ||
| e2/e4 | 0 (0) | 0 (0) | ||
| e3/e3 | 31 (59) | 38 (84) | ||
| e3/e4 | 20 (38) | 4 (9) | ||
| e4/e4 | 0 (0) | 0 (0) | ||
| Presence of APOE-e4 allele, N (%) | Χ2 = 10.95 (1) | 0.001 | ||
| e4 | 20 (38) | 4 (9) | ||
| no e4 | 33 (62) | 41 (91) |