Table 2.

Summary of miRNAs involved in EGFR-TKI resistance in NSCLC

miRNA name	Expression in resistant NSCLC	Targets	References
miR-21	Up	PDCD4, MDR1, PTEN and bcl-2	[171-173]
miR-103 and -203	Down	PKC-ε, SRC, Dicer.	[174,175]
miR-126	Down	PIK3R2, CRK, VEGF	[176-178]
miR-128b	Down	EGFR	[179]
miR-214	Up	PTEN, p38, MAPK	[180,181]
miR-221, miR-222	Up	PTEN, APAF-1, BIM, TIMP3	[174,182]
MiR-145	Down	c-MYC, AKT, ERK, OCT4	[183-185]