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STAT3Δβ/Δβ mice show earlier papilloma onset but unaltered tumor load. STAT3WT/WT and STAT3Δβ/Δβ mice were treated with DMBA/TPA as described and observed for squamous cell papilloma (SCP) development for 42 weeks. A. Shows the percentage of papilloma-free mice. Grey line, STAT3WT/WT mice (n=15); black line, STAT3Δβ/Δβ mice (n=14). B. Shows the number and mean diameter±SD of SCPs per mouse. C. Representative SCPs images from mice of the indicated genotypes.
