Table 4.
Grades of PMP mucin with percentage absolute dissolution after treatment with 300 μg/ml bromelain + 250 mM N-Acetyl Cystein in TRIS buffer at 37 deg Celsius for 3 hours (in vitro investigation)
| Mucin grade | Total Number (%) | Mean HI ± SD | Dissolution (%) ± SD | Residue |
|---|---|---|---|---|
| SOFT | 22 (62) | 0.5221 ± 0.0433 | 100 ± 2.236 | NONE |
| SEMI HARD | 8 (20) | 1.0481 ± 0.1440 | 57.38 ± 3.114 | Soft tissues |
| HARD | 6 (18) | 1.5081 ± 0.0635 | 50 ± 1.789 | solid tissues |
Table 4 show the total number and percentage distribution of the three grades of mucin within the patient PMP sample with mean hardness index (HI) for each grade of mucin, along with mean absolute percentage disintegration. Dissolution with the mucolytic left no residues for soft mucin whilst some tissues remained for semi hard and hard mucin (in vitro investigation). Ratio: soft:semi hard:hard mucin = 3.0:1.0:1.0; HI = Hardness Index; SD = standard deviation.