Table 6.

Nett % dissolution of PMP mucin (normalised to control)

Parameter	Soft mucin (%)	Semi hard mucin (%)	Hard mucin (%)
In vitro dissolution (A)	90	57	50
In vivo dissolution (B)	80	34	20
Difference (A, B)	10	23	30

Table 6 shows a comparison of PMP mucin Nett percentage dissolution found in vitro to in vivo studies. The difference found for soft mucin is small (10%) compared to semi hard (23%) and hard mucin (30%). The differences between the in vitro and in vivo Nett disintegration is indicative of how much hydration forces along with time factor can influence disintegration of PMP mucin.