Figure 3.

DUOX1 was downregulated and hypermethylated in primary HCC tissues. The expression of DUOX1 in HCC tissues and adjacent non-tumor tissues was determined by real-time PCR. A: 78 pairs of samples were from liver tissue, including tumor tissue and adjacent non-tumor tissue. B: The expression of DUOX1 mRNA in different Edmondson stage of primary HCC tissues. C: The expression of DUOX1 mRNA in different TNM stage of primary HCC tissues. D: The methylation status of DUOX1 promoter in primary HCC tissues and adjacent non-tumor tissues was detected by MSP. Representative results were shown. “T” indicates tumor tissues and “N” represents adjacent non-tumor tissues. The gels have been run under the same experimental conditions.