Table 1.
Correlation of DUOX1 mRNA expression with clinical characteristics in 78 patients with HCC
| Characteristics | No. of patients | Relative Duox1 mRNA levels(log10) (Mean ± SEM) | P value |
|---|---|---|---|
| Gender | 0.442 | ||
| Male | 59 | 0.3456 ± 0.0801 | |
| Female | 19 | 0.4362 ± 0.1128 | |
| Age (years) | 0.062 | ||
| ≤ 50 | 33 | 0.4706 ± 0.1173 | |
| > 50 | 45 | 0.2922 ± 0.0755 | |
| HBsAg | 0.123 | ||
| Positive | 66 | 0.3037 ± 0.7350 | |
| Negative | 12 | 0.7198 ± 0.1063 | |
| HBeAg | 0.585 | ||
| Positive | 25 | 0.2425 ± 0.1088 | |
| Negative | 53 | 0.4267 ± 0.0824 | |
| Tumor size (cm) | 0.323 | ||
| ≤ 5 cm | 18 | 0.4131 ± 0.1195 | |
| > 5 cm | 35 | 0.4869 ± 0.1063 | |
| Edmondson stage | 0.677 | ||
| I | 13 | 0.3987 ± 0.1145 | |
| II | 50 | 0.3960 ± 0.0852 | |
| III | 15 | 0.2465 ± 0.1737 | |
| TNM stage | 0.049 | ||
| I | 20 | 0.1644 ± 0.1149 | |
| II | 26 | 0.6145 ± 0.1212 | |
| III | 16 | 0.3574 ± 0.1438 | |
| IV | 15 | 0.2333 ± 0.1410 |
HCC hepatocellular carcinoma, HBsAg hepatitis B surface antigen, HBeAg hepatitis B e antigen, TNM tumor–node–metastasis.