Table 2.
Relationship between clinicopathological features and the expression of Wnt2 and sFRP4
| Variables | Wnt2 expression | sFRP4 expression | ||||
|---|---|---|---|---|---|---|
|
|
|
|||||
| low | high | P-value | low | high | P-value | |
| Age (years) | ||||||
| < 60 | 15 | 25 | 0.042* | 22 | 18 | 0.855 |
| ≥ 60 | 29 | 20 | 26 | 23 | ||
| Gender | ||||||
| female | 14 | 19 | 0.351 | 14 | 19 | 0.081 |
| male | 30 | 27 | 35 | 22 | ||
| Location | ||||||
| head | 29 | 24 | 0.146 | 34 | 19 | 0.091 |
| body/rear | 11 | 18 | 13 | 16 | ||
| Size | ||||||
| < 4 | 26 | 25 | 0.736 | 31 | 20 | 0.208 |
| ≥ 4 | 18 | 20 | 18 | 20 | ||
| Differentiation | ||||||
| well | 0 | 1 | 0.573 | 0 | 1 | 0.215 |
| moderate | 29 | 27 | 30 | 26 | ||
| poor | 11 | 12 | 16 | 7 | ||
| AJCC stage | ||||||
| stage I | 27 | 13 | 0.008* | 23 | 17 | 0.280 |
| stage II | 16 | 31 | 26 | 21 | ||
| stage IV | 1 | 1 | 0 | 2 | ||
| PNI | ||||||
| positive | 16 | 21 | 0.371 | 21 | 16 | 0.713 |
| negative | 28 | 25 | 28 | 25 | ||
| LNM | ||||||
| positive | 31 | 20 | 0.029* | 29 | 22 | 0.452 |
| negative | 12 | 21 | 16 | 17 | ||
Note: LNM: lymph node metastasis; PNI: perineural invasion;
*
P < 0.05, statistically significant.