Table 2.
Fold differences in miRNAs between GSCs treated with 450 μM TMZ alone and in combination with 1 mg/ml and 2 mg/ml OLE
| mir-181b | miR-153 | miR-145 | miR-137 | let-7d | |
|---|---|---|---|---|---|
| 450 µM TMZ | |||||
| 2^(-Avg.(Delta(Ct)) | 0.088388 | 0.016289 | 0.080214 | 0.016289 | 0.046974 |
| 1 mg/ml OLE + 450 µM TMZ | |||||
| 2^(-Avg.(Delta(Ct)) | 9.958994 | 0.028676 | 0.056563 | 0.018149 | 0.004588 |
| Fold Change | 112.6732 | 1.7605 | 0.7051 | 1.1142 | 0.0977 |
| 95% CI | (0.00001, 492.25) | (0.00001, 4.51) | (0.00001, 1.79) | (0.00001, 2.59) | (0.00001, 0.26) |
| * P value | 0.0829 | 0.3133 | 0.7102 | 0.4842 | 0.1542 |
| 2 mg/ml OLE + 450 µM TMZ | |||||
| 2^(-Avg.(Delta(Ct)) | 1.503161 | 0.031034 | 0.583984 | 0.017027 | 0.143786 |
| Fold Change | 17.0063 | 1.9053 | 7.2803 | 1.0454 | 3.061 |
| 95% CI | (2.54, 31.47) | (0.00001, 3.99) | (0.00001, 15.22) | (0.00001, 2.68) | (0.00001, 7.35) |
| * P value | 0.0030 | 0.2173 | 0.0040 | 0.3944 | 0.4846 |
*
Evaluated with an independent sample T-test using RT2 Profiler PCR Array Data Analysis.