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. 2014 Aug 29;3(9):839–849. doi: 10.1242/bio.20149027

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© 2014. Published by The Company of Biologists Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Fig. 1. — (A) EJP traces of EJP during 0.2 Hz of stimulation at 0.5 mM [Ca2+] at muscle A36 for wildtype (n = 6) syp²⁸⁶/syp²⁸⁶ (n = 6) syp²⁸⁶/syp^Df124 (n = 6) and syp Rescue (n = 5). (B) The mean EJP amplitude is significantly reduced in syp mutants relative to controls (C) while the miniature(m)EJP amplitude and frequency (not shown) remain unchanged. (D) Accordingly the Quantal Content is significantly reduced in syp mutants relative to controls. (E,F) The paired-pulse ratio for a 50 ms time interval reveals that syncrip mutants exhibit a decrease in vesicle release probability. n refers to the number of animals tested. (G) mini (m) EJP frequency is unchanged in syp mutants. Independent two-tailed Student's t-test; *** p<0.001 ** p<0.005 * p<0.05, n.s. p>0.05.