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. 2014 Sep 15;4:6353. doi: 10.1038/srep06353

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(a) Endogenous NMHC IIb was less accumulated in the spine neck of the FILIP-expressing hippocampal neurons. (b) The summarised data of 816 spines (the control) and 649 spines (the FILIP-expressing neurons) are shown; p < 0.00001 (Fisher's exact test, two-tailed). (c) Exogenous NMHC IIb (exo-NMHC IIb) rescued the spine elongation due to FILIP overexpression in the hippocampal neurons. (d) The summarised data of 362 spines (FILIP-/exo-NMHC IIb–), 712 spines (FILIP-/exo-NMHC IIb+), 555 spines (FILIP+/exo-NMHC IIb–) and 828 spines (FILIP+/exo-NMHC IIb+) are shown. In each case, spines were selected from 5 neurons; * p = 0.00386, ** p < 0.00001 (Welch's t-test, two-tailed).