Table 5.

Statistical diagnostic measures for miR-197, miR-146b, miR-181d and miR-99a in identifying non-alcoholic fatty liver disease

miRNA	Cut-off value	SEN (95%CI)	SPE (95%CI)	PPV (95%CI)	NPV (95%CI)
miR-197	≤ -1.0144	60.0 (36.1-80.9)	95.0 (75.1-99.9)	92.3 (64.0-99.8)	70.4 (49.8-86.2)
miR-146b	≤ -0.7689	55.0 (31.6-76.9)	100.0 (83.0-100.0)	100.0 (71.3-100.0)	69.0 (49.2-84.7)
miR-181d	≤ -0.2861	70.0 (45.7-88.0)	85.0 (62.1-96.6)	82.4 (56.6-96.0)	73.9 (51.6-89.7)
miR-99a	≤ -0.1562	65.0 (40.8-84.5)	95.0 (75.1-99.2)	92.9 (66.1-98.8)	73.1 (52.2-88.4)

SEN: Sensitivity; SPE: Specifity; PPV: Positive predictive value; NPV: Negative predictive value.