Table 5.
Crude event rates, and age-and sex-adjusted hazard ratios for incident CVD/CHD death (after cycle 6) according to the pattern of change in left ventricular geometry (from cycle 5 to 6).
Change in LV geometry from exam 5 to exam 6 |
Events after exam 6 / individuals at risk |
Risk | Age- and sex-adjusted HR (95% CI) |
P-value |
Reference | 44/1058 | 4.2% | 1 | |
Improved | 31/439 | 7.1% | 1.39 (0.88, 2.21) | 0.16 |
Worsened | 43/479 | 9.0% | 1.59 (1.04, 2.43) | 0.03 |
High risk (Remained EH/CH*) | 22/129 | 17.1% | 3.42 (2.04, 5.74) | <0.0001 |
Individuals with eccentric hypertrophy (EH) at exam 5 and exam 6; or with concentric hypertrophy (CH) at exam 5 and exam 6. HR, hazard ratio, CVD denotes cardiovascular disease; CHD coronary heart disease