Fig. 3. The preventive (A, B) and therapeutic (C, D) effect of TT-rhB7-H4IgV vaccine to transplanted SP2/0 tumor of BALB/c mice. (A, C) Growth of SP2/0 tumors vaccinated with TT-rhB7-H4IgV, rhB7-H4IgV, or only adjuvant. The number of animals that developed tumors/total number of animals is indicated in parenthesis. (B, D) Life span of BALB/c mice after challenge of SP2/0 cells. The survival data were subjected to Kaplan-Meier analysis. *Statistically significant difference compared with the control adjuvant mice (P ＜ 0.05).
