Fig. 2. ZBTB3 knockdown causes apoptosis. (A, B) The effects of ZBTB3 knockdown on cell apoptosis in MeWo, CORL113, and T47D cells. Values (percentage of apoptotic cells) represent mean ± SD of three independent experiments performed three times; **P ＜ 0.01 vs. control shRNA. (C) The effects of ZBTB3 knockdown on caspase-3 activity in several cancer cell lines. Values represent mean ± SD of independent experiments performed three times; **P ＜ 0.01 vs. control shRNA. (D) Expression of apoptotic proteins in cells with ZBTB3 knocked down.
