| Methods | Twelve-week double-blind study | |
| Participants | Outpatients suffering from a major depressive episode, recurrent depression or disthymia according to DSM-III-R, with a score of at least 25 on the HARD and on the FARD scales. Age range: 25-65 years. Exclusion criteria: not reported. |
|
| Interventions | Fluoxetine: 104 participants. Tianeptine: 102 participants. Fluoxetine dose: 20 mg/day. Tianeptine dose: 37.5 mg/day. Benzodiazepines were allowed only if severe anxiety or sleep disorders |
|
| Outcomes | HARD (humeur, angoisse, ralentissement, danger), FARD (Ferreri anxiety rating diagram), HSCL (Hopkins Symptom check-list) | |
| Notes | Funding: by Academy | |
| Risk of bias | ||
| Item | Authors’ judgement | Description |
| Allocation concealment? | Unclear | B - Unclear |
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.