| Methods | Four-week randomised, double-blind study. | |
| Participants | Outpatients fulfilling Kielholz/Poeldinger scheme for depression, with a score of at least 14 on the HDRS-14. Age range: 21-67 years old. Exclusion criteria: not stated. |
|
| Interventions | Fluoxetine: 73 participants. Maprotiline : 69 participants. Fluoxetine dose: 40 mg/day. Maprotiline dose: 75 mg/day. Only chloral hydrate and oxazepam were allowed for insomnia. |
|
| Outcomes | Hamilton Rating Scale for Depression (HDRS-14), CGI-I. | |
| Notes | Funding: unclear | |
| Risk of bias | ||
| Item | Authors’ judgement | Description |
| Allocation concealment? | Unclear | B - Unclear |
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