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. Author manuscript; available in PMC: 2014 Sep 15.
Published in final edited form as: Cochrane Database Syst Rev. 2012 Apr 18;4:CD007145. doi: 10.1002/14651858.CD007145.pub2
Methods Randomised controlled trial, set in prenatal care at the University of Washington Obstetrics Clinics
Participants Pregnant women with obesity (prepregnancy weight > 120% of ideal body weight) and diagnosed with gestational diabetes, recruited at 28 weeks’ gestation
Interventions All patients were hospitalised for 2-week duration in the metabolic ward
Intervention; calorie-restricted (n = 7): during the 1st week, the women consumed normal diet with 2400 kcal/day; 50% CHO, 30% fat and 20% protein with 11 gm of total dietary fibre per 500 kcal. During the 2nd week, the women were placed on 1200 kcal/day diet. This reduction was accomplished by decreasing portion sizes without changing other features of diet
Control (n = 5): during the 1st week, the patients consumed identical diet as the intervention group; 2400 kcal/day, and continued on the same diet (2400 kcal/day) during the 2nd week
Outcomes Metabolic indices: fasting plasma glucose, OGTT, insulin, triglyceride, free fatty acids, glycerol, ß-hydroxybutyrate, and urine ketones
We have not included outcome data from this hospital inpatient study in the analyses in the review
Notes Age (calorie-restricted, control): 30 ± 4, 36 ± 5 years.
Risk of bias
Bias Authors’ judgement Support for judgement
Random sequence generation (selection bias) Unclear risk No information provided.
Allocation concealment (selection bias) Unclear risk No information provided.
Blinding (performance bias and detection bias)
All outcomes
Unclear risk No information provided.
Incomplete outcome data (attrition bias)
All outcomes
Unclear risk No information provided.
Selective reporting (reporting bias) Unclear risk Could not determine.
Other bias Unclear risk No information provided.