Methods | Randomised controlled trial, set in prenatal care at the University of Washington Obstetrics Clinics | |
Participants | Pregnant women with obesity (prepregnancy weight > 120% of ideal body weight) and diagnosed with gestational diabetes, recruited at 28 weeks’ gestation | |
Interventions | All patients were hospitalised for 2-week duration in the metabolic ward Intervention; calorie-restricted (n = 7): during the 1st week, the women consumed normal diet with 2400 kcal/day; 50% CHO, 30% fat and 20% protein with 11 gm of total dietary fibre per 500 kcal. During the 2nd week, the women were placed on 1200 kcal/day diet. This reduction was accomplished by decreasing portion sizes without changing other features of diet Control (n = 5): during the 1st week, the patients consumed identical diet as the intervention group; 2400 kcal/day, and continued on the same diet (2400 kcal/day) during the 2nd week |
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Outcomes | Metabolic indices: fasting plasma glucose, OGTT, insulin, triglyceride, free fatty acids, glycerol, ß-hydroxybutyrate, and urine ketones We have not included outcome data from this hospital inpatient study in the analyses in the review |
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Notes | Age (calorie-restricted, control): 30 ± 4, 36 ± 5 years. | |
Risk of bias | ||
Bias | Authors’ judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | No information provided. |
Allocation concealment (selection bias) | Unclear risk | No information provided. |
Blinding (performance bias and detection bias) All outcomes |
Unclear risk | No information provided. |
Incomplete outcome data (attrition bias) All outcomes |
Unclear risk | No information provided. |
Selective reporting (reporting bias) | Unclear risk | Could not determine. |
Other bias | Unclear risk | No information provided. |