Methods	RCT, D, parallel groups Gel lightly massaged into skin three times daily, and kept dry for 6 to 8 hours Assessed at baseline, 3, 10, days
Participants	Peri and extra-articular inflammatory diseases N = 100 M 32, F 68 Mean age49 years Baseline spontaneous pain ≥40 mm
Interventions	DHEP lecithin gel, 3 × 5 g (= 65 mg) daily, n = 50 DHEP gel, 3 × 5 g (= 65 mg) daily, n = 50
Outcomes	PGE: 4 point scale (responder = “good” or “excellent”) Pain on movement:Mean Adverse events Withdrawals
Notes	Oxford Quality Score: R1, DB1, W1. Total = 3/5 Oxford Validity Score: 13/16
Risk of bias
Bias	Authors’ judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Not described
Allocation concealment (selection bias)	Unclear risk	Not described
Blinding (performance bias and detection bias) All outcomes	Unclear risk	Not described