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. Author manuscript; available in PMC: 2014 Sep 15.
Published in final edited form as: Cochrane Database Syst Rev. 2011 Jun 15;(6):CD004718. doi: 10.1002/14651858.CD004718.pub3
Methods Allocation: cluster randomised with 46 GP practices.
Blinding: open study.
Setting: community health centre, London, UK.
Follow-up: over 12 months.
Participants Diagnosis: psychosis (CAARMS*)
N=113.
Age: mean age 23 years.
Sex: 81 M, 32 F.
Excluded: participants with a history of contact with mental health services for psychosis for more than 6 months or antipsychotic treatment for more than a month.
History: first-episode psychosis.
Interventions 1. GP education in early detection with access to LEO-CAT. N=23 practices, N=50 participants.

2. Usual care, with access to LEO-CAT. N=23 practices, N=63 participants
Outcomes Hospitalisation.
Referred to Mental Health Services by Accident and Emergency or Emergency Health services
Notes *Comprehensive Assessment of At-Risk Mental States (CAARMS) (Yung 2005).
LEO-CAT- Lambeth Early Onset Crisis Assessment Team. GP practices randomised into the intervention group received both the GP education training and direct access to the LEO CAT team for referrals.
Risk of bias
Bias Authors’ judgement Support for judgement
Adequate sequence generation? Unclear risk Randomised, no further details.
Allocation concealment? Unclear risk No details.
Blinding?
All outcomes
High risk Open study.
Incomplete outcome data addressed?
All outcomes
High risk Study attrition not reported.
Free of selective reporting? Unclear risk No details.
Free of other bias? Unclear risk No details.