TABLE 1.
Proportion of cells containing foci and number of nuclear foci containing both BLM and hp150 in HeLa cellsa
| Treatment | % of cells containing:
|
Mean no. of foci/cell (range)
|
% of cells containing BLM and CAF-1 colocalizing foci
|
Mean no. of BLM and CAF-1 colocalizing foci/cell | ||||
|---|---|---|---|---|---|---|---|---|
| BLM foci | CAF-1 foci | BLM foci | CAF-1 foci | 0 foci | 1-5 foci | >5 foci | ||
| None | 36 | 9 | 4.2 (0-27) | 3.1 (0-29) | 93 | 6 | 1 | 1.8 |
| HU (5 mM) | 85 | 68 | 22.2 (0-51) | 29.6 (0-54) | 60 | 32 | 8 | 7.6 |
| MNNG (5 M) | 94 | 57 | 26.8 (0-66) | 23.3 (0-49) | 64 | 29 | 7 | 6.9 |
| UV | 45 | 37 | 6.8 (0-30) | 6.3 (0-32) | 75 | 23 | 2 | 4.2 |
a
In each case, 150 cells were scored.