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. Author manuscript; available in PMC: 2015 Feb 1.
Published in final edited form as: Eur J Neurosci. 2013 Nov 18;39(4):548–556. doi: 10.1111/ejn.12426

Fig. 4.

Fig. 4

MPH-treated mice lack ethanol-induced LTD and exhibit reversed HFS-induced plasticity under ethanol (EtOH). (A, B) Field potential recordings in the dorsolateral striatum evoked by stimulation that induces half-maximal PS amplitudes. (A) A 10 min application of 50 mM EtOH inhibits PS amplitude in control but not MPH-treated mouse slices. (B) Bath-applied 50 mM EtOH reverses the direction of HFS-induced plasticity seen in MPH-treated mice. (C) Voltammetry shows that evoked [DA]o is similar across treatment groups both before and during the bath application of 50 mM EtOH. Blue, control mice; orange, MPH-treated mice.